diff --git a/.github/config-schema.json b/.github/config-schema.json
index e3cb4b3a..2733295f 100644
--- a/.github/config-schema.json
+++ b/.github/config-schema.json
@@ -1396,6 +1396,9 @@
     },
     "python": {
       "default": {
+        "detect_env_vars": [
+          "VIRTUAL_ENV"
+        ],
         "detect_extensions": [
           "py"
         ],
@@ -5258,6 +5261,15 @@
           "items": {
             "type": "string"
           }
+        },
+        "detect_env_vars": {
+          "default": [
+            "VIRTUAL_ENV"
+          ],
+          "type": "array",
+          "items": {
+            "type": "string"
+          }
         }
       },
       "additionalProperties": false
diff --git a/docs/config/README.md b/docs/config/README.md
index 7cc1008d..2246edcc 100644
--- a/docs/config/README.md
+++ b/docs/config/README.md
@@ -3673,6 +3673,7 @@ By default, the module will be shown if any of the following conditions are met:
 | `detect_extensions`  | `['py']`                                                                                                     | Which extensions should trigger this module                                            |
 | `detect_files`       | `['.python-version', 'Pipfile', '__init__.py', 'pyproject.toml', 'requirements.txt', 'setup.py', 'tox.ini']` | Which filenames should trigger this module                                             |
 | `detect_folders`     | `[]`                                                                                                         | Which folders should trigger this module                                               |
+| `detect_env_vars`    | `["VIRTUAL_ENV"]`                                                                                            | Which environmental variables should trigger this module                               |
 | `disabled`           | `false`                                                                                                      | Disables the `python` module.                                                          |
 
 ::: tip
diff --git a/src/configs/python.rs b/src/configs/python.rs
index bcfa713d..3654fa82 100644
--- a/src/configs/python.rs
+++ b/src/configs/python.rs
@@ -21,6 +21,7 @@ pub struct PythonConfig<'a> {
     pub detect_extensions: Vec<&'a str>,
     pub detect_files: Vec<&'a str>,
     pub detect_folders: Vec<&'a str>,
+    pub detect_env_vars: Vec<&'a str>,
 }
 
 impl<'a> Default for PythonConfig<'a> {
@@ -45,6 +46,7 @@ impl<'a> Default for PythonConfig<'a> {
                 "__init__.py",
             ],
             detect_folders: vec![],
+            detect_env_vars: vec!["VIRTUAL_ENV"],
         }
     }
 }
diff --git a/src/modules/python.rs b/src/modules/python.rs
index 29974163..d531362b 100644
--- a/src/modules/python.rs
+++ b/src/modules/python.rs
@@ -19,9 +19,10 @@ pub fn module<'a>(context: &'a Context) -> Option<Module<'a>> {
         .set_folders(&config.detect_folders)
         .is_match();
 
-    let is_venv = context.get_env("VIRTUAL_ENV").is_some();
+    let has_env_vars =
+        !config.detect_env_vars.is_empty() && context.detect_env_vars(&config.detect_env_vars);
 
-    if !is_py_project && !is_venv {
+    if !is_py_project && !has_env_vars {
         return None;
     };
 
@@ -371,6 +372,42 @@ Python 3.7.9 (7e6e2bb30ac5fbdbd443619cae28c51d5c162a02, Nov 24 2020, 10:03:59)
         dir.close()
     }
 
+    #[test]
+    fn with_different_env_var() -> io::Result<()> {
+        let dir = tempfile::tempdir()?;
+
+        let actual = ModuleRenderer::new("python")
+            .path(dir.path())
+            .env("MY_ENV_VAR", "my_env_var")
+            .config(toml::toml! {
+                [python]
+                detect_env_vars = ["MY_ENV_VAR"]
+            })
+            .collect();
+
+        let expected = Some(format!("via {}", Color::Yellow.bold().paint("🐍 v3.8.0 ")));
+
+        assert_eq!(actual, expected);
+        dir.close()
+    }
+
+    #[test]
+    fn with_no_env_var() -> io::Result<()> {
+        let dir = tempfile::tempdir()?;
+
+        let actual = ModuleRenderer::new("python")
+            .path(dir.path())
+            .env("VIRTUAL_ENV", "env_var")
+            .config(toml::toml! {
+                [python]
+                detect_env_vars = []
+            })
+            .collect();
+
+        assert_eq!(actual, None);
+        dir.close()
+    }
+
     #[test]
     fn with_active_venv_and_prompt() -> io::Result<()> {
         let dir = tempfile::tempdir()?;