diff --git a/CHANGELOG-nightly.md b/CHANGELOG-nightly.md
index f240b3c..665d430 100644
--- a/CHANGELOG-nightly.md
+++ b/CHANGELOG-nightly.md
@@ -2,6 +2,7 @@
 
 Note: Breaking changes between versions are indicated by "💥".
 
+- 💥[Improvement] Drop Python 3.5 compatibility.
 - [Bugfix] Fix docker-compose project name in development on nightly branch.
 - 💥[Bugfix] No longer track the Tutor version number in resource labels (and label selectors, which breaks the update of Deployment resources), but instead do so in resource annotations.
 - [Bugfix] Make it possible for plugins to implement the "caddyfile" patch without relying on the "port" local variable.
diff --git a/setup.py b/setup.py
index 982c941..2f77aaa 100644
--- a/setup.py
+++ b/setup.py
@@ -52,7 +52,7 @@ setup(
     long_description_content_type="text/x-rst",
     packages=find_packages(exclude=["tests*"]),
     include_package_data=True,
-    python_requires=">=3.5",
+    python_requires=">=3.6",
     install_requires=load_requirements(),
     entry_points={"console_scripts": ["tutor=tutor.commands.cli:main"]},
     classifiers=[
@@ -61,7 +61,6 @@ setup(
         "License :: OSI Approved :: GNU Affero General Public License v3",
         "Operating System :: OS Independent",
         "Programming Language :: Python",
-        "Programming Language :: Python :: 3.5",
         "Programming Language :: Python :: 3.6",
         "Programming Language :: Python :: 3.7",
         "Programming Language :: Python :: 3.8",